Adan,
You apparently do not want to shoot film, but if you are willing to go back a few decades, you could outfit yourself with a Norita 66 system. I am guessing that weight and handling would be similar with exception of the complete lack of electronics in the Norita. But the Norita does handle like a large 35mm SLR, very different from the Pentax 67 or Pentacon 6. I routinely shoot my Norita 66 hand-held at 1/15 sec with good results as it is very well damped. The viewfinder is bright and easy to focus. All in all just like using a Nikon F or Canon F1 on steroids.
Here is my kit...
The Norita has a complete selection of lens from 40mm to 400m including a leaf-shutter lens. While the lenses are not multi-coated, they are extremely high-quality.
For $10,000 you could buy two complete Norita 66 systems and Imacon scanner and plenty of film.
The Leica S2 really appeales to me, in fact, I want a pair plus lenses very badly, but when I consider the amount of film and processing $100,000 will buy not mention the latest and greatest scanner, it is a reality check. Then add in the periphery costs in upgraded computers, software and storage, I really doubt that the Leica S2 is in my future.
I work in very remote sections of Australia, often days and weeks from any mains supply for powering electrics, so the Norita's work very well for me. Completely mechanical and I am able to do a complete overhaul in the bush if I get one of them flooded or broken down.
But I still would love to justify a pair of S2's. If the S2 is all we hope it is, it would be a perfect tool of the working field photographer. I hope that Leica produces some really fast glass, like a f1.4 normal lens and lots of f2.0 primes on either side. A nice bevy of long telephotos, 400, 600 and 800, would be on my wish-list. But then I would never be able to afford any of these optics, so no point listening to me.